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Treatment of Tislelizumab-Induced Toxic Epidermal Necrolysis and Agranulocytosis: A Case Report and Literature Review.

Yanshi ZhouHonghao XueChenghua LuYemin ZhangQingyuan WuJun ZhangShiyun XieXiangqian XuXiaoyan Guo
Published in: Current drug safety (2024)
Effective management of severe immune-related side effects from tislelizumab, including TEN and agranulocytosis, can be partly achieved through steroids, gamma globulin, GCSF, and antibiotics. This strategy not only alleviates these adverse effects, but also potentially improves tumor conditions, highlighting the crucial role of vigilant monitoring and management in immunotherapy.
Keyphrases
  • drug induced
  • high glucose
  • diabetic rats
  • mouse model
  • oxidative stress
  • combination therapy
  • wound healing
  • stress induced