Biomarkers to Distinguish Bacterial From Viral Pediatric Clinical Pneumonia in a Malaria-Endemic Setting.

Michael A GilletteD R ManiChristopher UschnigKarell G PelléLola MadridSozinho AcácioMiguel LanaspaPedro AlonsoClarissa ValimSteven A CarrStephen F SchaffnerBronwyn MacInnisDanny A MilnerQuique BassatDyann F Wirth

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)

Blood protein signatures highly associated with neutrophil biology reliably differentiated bacterial pneumonia from other causes. With appropriate technology, these markers could provide the basis for a rapid diagnostic for field-based triage for antibiotic treatment of pediatric pneumonia.

Keyphrases

emergency department
community acquired pneumonia
sars cov
respiratory failure
gene expression
small molecule
amino acid
protein protein
binding protein
plasmodium falciparum
quantum dots
mechanical ventilation