Implant for Augmentation of Cerebral Blood Flow Trial-1 (ImpACT-1). A single-arm feasibility study evaluating the safety and potential benefit of the Ischemic Stroke System for treatment of acute ischemic stroke.

Dheeraj KhuranaSubhash KaulDietmar SchneiderAttila CsanyiIlona AdamNasli R IchaporiaBernd GriewingLaszlo CsibaAttila ValikovicsVinod PuriHans Christoph DienerStefan SchwabAndreas HetzelNatan Bornsteinnull null

Published in: PloS one (2019)

The implantation procedure and the SPG stimulation, initiated within 24hr from stroke onset, are feasible, safe, and tolerable. The results call for a follow-up randomized trial (funded by BrainsGate; clinicaltrials.gov number, NCT03733236).

Keyphrases

acute ischemic stroke
cerebral blood flow
atrial fibrillation
soft tissue
clinical trial
study protocol
phase iii
phase ii
risk assessment
combination therapy
open label
brain injury