Ultrastructural changes during osteogenic differentiation in mesenchymal stromal cells cultured in alginate hydrogel.

Jakub GrzesiakAgnieszka ŚmieszekKrzysztof Marycz

Published in: Cell & bioscience (2017)

The ECM synthesis and deposition during the osteogenic differentiation of MSC involves cellular programmed death. The small membrane vesicles become the mineralization sites of formed bone ECM.

Keyphrases

bone marrow
extracellular matrix
mesenchymal stem cells
wound healing
tissue engineering
bone mineral density
drug delivery
endothelial cells
hyaluronic acid
soft tissue
bone regeneration
electron microscopy