Login / Signup

Cilia loss on distinct neuron populations differentially alters cocaine-induced locomotion and reward.

Thomas EverettTyler W Ten EyckChang-Hung WuAmanda L ShelowitzSofia M StansburyAlexandra FirekBarry SetlowJeremy C McIntyre
Published in: Journal of psychopharmacology (Oxford, England) (2023)
Combined with previous findings using amphetamine, our results show that behavioral effects of cilia ablation are cell- and drug type-specific, and that neuronal cilia contribute to modulation of both the locomotor-inducing and rewarding properties of cocaine.
Keyphrases
  • prefrontal cortex
  • spinal cord injury
  • single cell
  • drug induced
  • high glucose
  • diabetic rats
  • oxidative stress
  • radiofrequency ablation
  • genetic diversity