Multimethod quantitative benefit-risk assessment of treatments for moderate-to-severe osteoarthritis.

Jonathan Mauer Kristin Bullock Stephen Watt Ed Whalen Leo Russo Rod Junor John D Markman A Brett Hauber Tommi Tervonen

Published in: British journal of clinical pharmacology (2022)

The multimethod approach to quantitative benefit-risk modelling allowed the interpretation of clinical data from the patient perspective while accounting for uncertainties in the clinical effect estimates and imprecision in patient preferences.

Keyphrases

risk assessment
case report
high resolution
electronic health record
big data
machine learning
high intensity
human health
mass spectrometry
climate change
decision making