Systematic Review: Monoclonal Antibody-Induced Subacute Cutaneous Lupus Erythematosus.

Chrissy BoltonYifan ChenRachel HawthorneIanthe R M SchepelElinor HarrissSilke C HofmannSpencer EllisAlexander ClarkeHelena WaceBlanca MartinJoel Smith

Published in: Drugs in R&D (2021)

We present the first systematic review characterising mAb-induced SCLE with respect to triggers, clinical signs, laboratory findings, prognosis and treatment approaches. We identify elevated rates associated with the use of checkpoint inhibitors and anti-TNFɑ agents.

Keyphrases

systematic review
monoclonal antibody
meta analyses
high glucose
diabetic rats
systemic lupus erythematosus
rheumatoid arthritis
drug induced
oxidative stress
endothelial cells