Genomic variation associated with carcinoma showing thymus-like elements (CASTLE) in thyroid gland.
Lin JiangWei-Hui ZhengChao ChenPublished in: Laryngoscope investigative otolaryngology (2022)
CASTLE tumors contain unique tumor driver gene mutations. The information about mutations in several novel genes obtained in this study may contribute to unraveling the molecular mechanisms responsible for the emergence of thyroid CASTLE tumors and help formulating possible in-roads for treatment.