Radio-protective efficacy of Gymnema sylvestre on Pangasius sutchi against gamma (60Co) irradiation.
Pamela SinhaKantha Devi ArunachalamSanthosh Kumar NagarajanThirumurthy MadhavanArumugam R JayakumarMohamed Saiyad MusthafaPublished in: International journal of radiation biology (2021)
Predictive assessment was carried out by docking of Ami, various components of GS with p53, NF-κβ cells and Rad51 proteins structures responsible for CCA, apoptosis and repair mechanism. These structural proteins were docked with other structural proteins like USP7, TNF-α and partner and localizer of BRCA2 associated (PALB2/BRCA2) complex which made us perform these systemic efforts to find the functional activity of these known radio-protectants.
Keyphrases
- cell cycle arrest
- induced apoptosis
- oxidative stress
- pi k akt
- signaling pathway
- endoplasmic reticulum stress
- cell death
- rheumatoid arthritis
- acute myocardial infarction
- dna damage
- high resolution
- dna repair
- lps induced
- heart failure
- quality improvement
- inflammatory response
- nuclear factor
- cell proliferation
- immune response
- protein protein
- percutaneous coronary intervention