Ratio and index of Neurofilament light chain indicate its origin in Guillain-Barré Syndrome.
Péter KörtvélyessyJens KuhleEmrah DüzelStefan VielhaberChristian SchmidtAnnika HeiniusFrank LeypoldtBurkhart SchravenDirk ReinholdDavid LeppertAlexander GoihlPublished in: Annals of clinical and translational neurology (2020)
These results demonstrate that the PNS is a relevant contributor to sNfL levels and that the distribution can be identified by a lowered NfL CSF/serum ratio of NfL index. Furthermore, acute or subacute polyneuropathies are likely confounding factors in interpreting sNfL levels in CNS diseases.