Early Impairment of Insulin Sensitivity, β-Cell Responsiveness, and Insulin Clearance in Youth with Stage 1 Type 1 Diabetes.

Alfonso Galderisi Antoinette M Moran Carmella Evans-MolinaMariangela MartinoNicola Santoro Sonia Caprio Claudio Cobelli

Published in: The Journal of clinical endocrinology and metabolism (2021)

Presymptomatic Stage 1 T1D in youth is associated with reduced insulin sensitivity and lower β-cell responsiveness, and the presence of blunted insulin clearance.

Keyphrases

type diabetes
glycemic control
single cell
physical activity
mental health
cell therapy
young adults
cardiovascular disease
insulin resistance
metabolic syndrome