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Evidences of neurological injury caused by COVID-19 from glioma tissues and glioma organoids.

Huimin HuChen WangRui TaoBohan LiuDazhao PengYankun ChenWei Zhang
Published in: CNS neuroscience & therapeutics (2024)
Gliomas had inherent traits that render them susceptible to SARS-CoV-2 infection, leading to their representability of COVID-19 neurological symptoms. This established a biological foundation for the rationality and feasibility of utilization of glioma organoids as research and blocking drug testing model in SARS-CoV-2 infection within the central nervous system.
Keyphrases
  • coronavirus disease
  • sars cov
  • respiratory syndrome coronavirus
  • gene expression
  • genome wide
  • emergency department
  • dna methylation
  • induced pluripotent stem cells
  • brain injury
  • subarachnoid hemorrhage