Development and Characterization of an Anti-PD-L1 Immunotoxin for Targeted Cancer Therapy.
Ali TakhtehMohammad Hosseininejad-ChafiAkbar OghalaieMahdi BehdaniFatemeh Kazemi-LomedashtPublished in: Current pharmaceutical biotechnology (2024)
This study provides a thorough characterization of the constructed IT, highlighting its potential as a therapeutic agent targeting PD-L1-expressing cancer cells. The results support the potential of this IT in cancer immunotherapy, emphasizing the need for further investigation into its efficacy and safety profiles.