Osteitis in Systemic Sclerosis: a nationwide case-control retrospective study (SCLEROS Study).

Cyril CosseSolen KernéisAlexis DechosalGregory PugnetMarie-Elise TruchetetPascal PriolletElisabeth DiotMickael MartinFrançois MaurierJean François ViallardChristian AgardBrigitte GranelSabine BerthierDorothée FagedetBénédicte WateletSégolène ToquetDavid Luque PazCloé GiretOlivier CerlesJérémie DionChristelle NguyenLoïc RaffrayJulien BertolinoWendy JourdeClaire Le JeunneLuc MouthonBenjamin Chaigne

Published in: Arthritis care & research (2020)

This study confirmed digital tip ulcers as an associated factor for osteitis, and revealed a high rate of functional sequelae. Antimicrobial therapy with oral fluoroquinolone or intravenous amoxicillin and beta-lactamase inhibitor are used as first-line antibiotherapy in SSc patients with osteitis.

Keyphrases

systemic sclerosis
interstitial lung disease
escherichia coli
case control
stem cells
multidrug resistant
low dose
mesenchymal stem cells
wound healing