Multifocal gastric adenocarcinoma in a patient with LRBA deficiency.

Nina BrataničJernej KovačKatka PoharKatarina Trebušak PodkrajšekAlojz IhanTadej BattelinoMagdalena Avbelj Stefanija

Published in: Orphanet journal of rare diseases (2017)

This is the first description of gastric cancer and malignant melanoma in a young adult with LRBA deficiency. The role of LRBA gene knockout in cancer development and its prognosis remains to be elucidated.

Keyphrases

young adults
papillary thyroid
childhood cancer
replacement therapy
case report
squamous cell carcinoma
squamous cell
copy number
genome wide
locally advanced
genome wide identification
transcription factor
smoking cessation