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CBGTPy: An extensible cortico-basal ganglia-thalamic framework for modeling biological decision making.

Matthew ClappJyotika BahugunaCristina GiossiJonathan E RubinTimothy VerstynenCatalina Vich
Published in: bioRxiv : the preprint server for biology (2023)
We introduce a toolbox for producing biologically realistic simulations of the cortico-basal ganglia-thalamic pathways during a variety of experimental tasks. The purpose is to foster the theory-experiment cycle, offering a tool for generating testable predictions of behavioral and neural responses that can be validated experimentally, in a framework that allows for simple updating as new experimental evidence emerges. We outline how our toolbox works and demonstrate its performance on a set of normative cognitive tasks.
Keyphrases
  • working memory
  • deep brain stimulation
  • decision making
  • molecular dynamics
  • monte carlo