Radiation-induced exosomes promote oral squamous cell carcinoma progression via enhancing SLC1A5-glutamine metabolism.

Rongchun YangSiyuan ZhangLixuan WangYingyao ChenXiaobing ChenJuan XiaXianyue RenBin ChengXijuan Chen

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2024)

Radiation-induced sEVs might promote the proliferation of unirradiated cancer cells by enhancing glutamine metabolism; this might be a novel molecular mechanism underlying radiation resistance in OSCC patients.

Keyphrases

radiation induced
radiation therapy
end stage renal disease
ejection fraction
newly diagnosed
mesenchymal stem cells
stem cells
prognostic factors
patient reported outcomes
patient reported