FREM predicts 10-year incident fracture risk independent of FRAX® probability: a registry-based cohort study.

William D LeslieSören MöllerMichael K SkjødtLin YanBo AbrahamsenLisa M LixEugene V McCloskeyHelena JohanssonNicholas C HarveyJohn A KanisKatrine Hass Rubin

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2022)

Higher FREM scores identified women and men at increased fracture risk even when adjusted for FRAX probability that included BMD; hence, FREM provides additional predictive information to FRAX. FRAX slightly underestimated 10-year fracture probability in those falling within the highest FREM quintile.

Keyphrases

hip fracture
cardiovascular disease
polycystic ovary syndrome
healthcare
pregnant women
middle aged
skeletal muscle
insulin resistance
breast cancer risk
social media
cervical cancer screening
community dwelling