Models for Predicting Response to Immunotherapy and Prognosis in Patients with Gastric Cancer: DNA Damage Response Genes.

Rui Dong Shuran Chen Fei Lu Ni Zheng Guisen Peng Yan Li Pan Yang Hexin Wen Quanwei Qiu Yitong Wang Huazhang Wu Mulin Liu

Published in: BioMed research international (2022)

We screened eight DDR-related genes (ZBTB7A, POLQ, CHEK1, NPDC1, RAMP1, AXIN2, SFRP2, and APOD) to establish a risk model, which can predict the prognosis of gastric cancer patients and guide the clinical implementation of immunotherapy.

Keyphrases

dna damage response
dna repair
primary care
healthcare
genome wide
quality improvement
oxidative stress
gene expression
dna damage
genome wide identification
bioinformatics analysis
dna methylation