Role of PKM2 in directing the metabolic fate of glucose in cancer: a potential therapeutic target.

Published in: Cellular oncology (Dordrecht) (2018)

The central role of PKM2 in directing the flow of carbon between catabolic (ATP-producing) and anabolic processes provides unique opportunities for extending the therapeutic window of currently available and/or novel anti-neoplastic agents.

Keyphrases

papillary thyroid
squamous cell
blood glucose
type diabetes
young adults
adipose tissue
climate change
skeletal muscle