Login / Signup

Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat.

David Martín-GálvezDenis Dunoyer de SegonzacMan Chun John MaAnne E KwitekDavid ThybertPaul Flicek
Published in: BMC genomics (2017)
Our results show that the use of functional regulatory conservation is a potentially effective approach to select strain-specific genomic regions associated with phenotypic differences among Lyon rats and could be extended to other systems.
Keyphrases
  • transcription factor
  • copy number
  • oxidative stress
  • genome wide
  • dna methylation