The cross talk between cervical carcinoma cells and vascular endothelial cells mediated by IL-27 restrains angiogenesis.
Bing ZhangFeng XieChun-Lin DongChun-Jie GuJiao ChengYuan WangXi-Zhong XuHong PuYi-Bo WuXiao-Wei QiDa-Jin LiJin-Jin YuMing-Qing LiPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2017)
This study indicates that IL-27 secreted by cervical carcinoma cells restricts the angiogenesis in a paracrine manner in the pathogenesis of cervical cancer.