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[Methodological basis for determining a person's age].

Yuri I PigolkinGalina V ZolotenkovaD P Berezovskiy
Published in: Sudebno-meditsinskaia ekspertiza (2020)
This paper presents a review of modern fundamental research studies investigating the age-related changes of connective, cartilage, nervous and bone tissues. A methodological and mathematical basis for the analysis of the obtained results is proposed. The conducted analysis enabled the formulation of a new scientific direction - the forensic medical determination of age in the identification of individuals in emergency situations with mass casualties. A scientifically grounded theory of digital forensic diagnostics of age, general regularities of development and some differences of age adaptation of connective, cartilage, nervous and bone tissues, including the phenomena of heterochronicity, heterotopy and heterogeneity resulted. The results of this research determine the direction of further research by improving the methods of quantitative age morphology, molecular autopsy, digital technologies and the formation of a technologically based concept for the registration of identifying biological features.
Keyphrases
  • healthcare
  • gene expression
  • emergency department
  • extracellular matrix
  • single molecule
  • molecularly imprinted
  • simultaneous determination
  • case control