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IL-17 is a Potential Therapeutic Target in a Rodent Model of Otitis Media with Effusion.

Nanfeng ZhangTingting QianShan SunWei CaoZhixian WangDanling LiuPeifan LiJingfang WuHuawei LiJianming Yang
Published in: Journal of inflammation research (2022)
IL-17 plays a key role in the pathogenesis of the OVA-induced OME rat model. IL-17 induced inflammatory responses via the Notch signaling pathway and targeting IL-17 might be an effective approach for OME therapy.
Keyphrases
  • signaling pathway
  • high glucose
  • diabetic rats
  • drug induced
  • cell proliferation
  • oxidative stress
  • endothelial cells
  • cancer therapy
  • induced apoptosis
  • endoplasmic reticulum stress
  • smoking cessation