Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis.

Xuling LiTingting ZhaoJunling GuZhe WangJing LinRushang WangTingting DuanZhenghai LiRuixue DongWeiming WangKin-Fong HongZhilong LiuWenbo HuangDingkun GuiHua ZhouYou-Hua Xu

Published in: Chinese medicine (2022)

Our findings demonstrated that flavonoids from Astragalus membranaceus ameliorated brain impairment, and its modulation on gut-brain axis plays a pivotal role. Our present study provided an alternative solution on preventing and treating diabetic cognition impairment.

Keyphrases

white matter
resting state
functional connectivity
cerebral ischemia
type diabetes
multiple sclerosis
signaling pathway
body mass index
wound healing