Effect of Concurrent Lidocaine, Remifentanil and Methylprednisolone Use on the Clinical Effect of Sugammadex under General Anaesthesia in Rats.
Tünay KandemirErbin KandemirTuğba AşkınSelda MusluGonca Oğuz TuncelSuheyla ÜnverPublished in: Turkish journal of anaesthesiology and reanimation (2019)
We suggest that remifentanil and methylprednisolone used concurrently with sugammadex lead to a decrease in sugammadex reversal effect by giving rise to decrease in its free and active concentrations probably via displacement in rats.