Effect of a high-calorie diet and constant light exposure on female reproduction, metabolism and immune inflammation: A comparative study of different mouse models.

Lingshan ZhangYukai LiuMing-Qing Li Xiao-Yong ZhuYingli Shi

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2021)

In conclusion, we found that unhealthy lifestyle determines the phenotype of reproductive endocrine, immune, and metabolic disorders. These findings can provide theoretical support for the subsequent study of PCOS-like features.

Keyphrases

weight loss
physical activity
mouse model
oxidative stress
metabolic syndrome
polycystic ovary syndrome
skeletal muscle
insulin resistance