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Effect of poly(ethylene glycol) content and formulation parameters on particulate properties and intraperitoneal delivery of insulin from PLGA nanoparticles prepared using the double-emulsion evaporation procedure.

Yusuf A HaggagAhmed M FaheemMurtaza M TambuwalaMohamed A OsmanSanaa A El-GizawyBarry O'HaganNigel IrwinPaul A McCarron
Published in: Pharmaceutical development and technology (2017)
Insulin-loaded NP prepared from 10% PEG-PLGA possessed therapeutically useful encapsulation and release kinetics when delivered by the IP route.
Keyphrases
  • drug delivery
  • type diabetes
  • cancer therapy
  • drug release
  • glycemic control
  • minimally invasive
  • insulin resistance
  • walled carbon nanotubes
  • wound healing