Cell fixation and preservation for droplet-based single-cell transcriptomics.

Jonathan AllesNikos KaraiskosSamantha D PraktiknjoStefanie GrosswendtPhilipp WahlePierre-Louis RuffaultSalah AyoubLuisa SchreyerAnastasiya BoltengagenCarmen BirchmeierRobert ZinzenChristine KocksNikolaus Rajewsky

Published in: BMC biology (2017)

We expect that the availability of a simple cell fixation method will open up many new opportunities in diverse biological contexts to analyse transcriptional dynamics at single-cell resolution.

Keyphrases

single cell
rna seq
minimally invasive
high throughput
gene expression
stem cells
mesenchymal stem cells