Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test.
Ila Marques Porto LinaresAntonio W ZuardiLuis C PereiraRegina H QueirozRaphael MechoulamFrancisco S GuimarãesJosé A CrippaPublished in: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) (2018)
Our findings confirm the anxiolytic-like properties of CBD and are consonant with results of animal studies describing bell-shaped dose-response curves. Optimal therapeutic doses of CBD should be rigorously determined so that research findings can be adequately translated into clinical practice.