Shared development of targeted therapies among autoimmune and inflammatory diseases: a systematic repurposing analysis.

Arthur PetitdemangeJulien BlaessJean SibiliaRenaud FeltenLaurent Arnaud

Published in: Therapeutic advances in musculoskeletal disease (2020)

Many targeted therapies are developed in several AIDs, reflecting the overlap of pathogenic pathways and potential of drug repurposing. This suggests that a revision of the current, clinically based classification of AIDs towards a more mechanistic-based taxonomy might be relevant.

Keyphrases

antiretroviral therapy
total knee arthroplasty
machine learning
multiple sclerosis
deep learning
oxidative stress
drug induced
emergency department
total hip arthroplasty
human health
risk assessment
adverse drug
electronic health record