Copy number variations identified in thyroid FNA specimens are associated with Hürthle cell cytomorphology.

Rita Abi-RaadManju L PrasadAdebowale J Adeniran Guoping Cai

Published in: Cancer cytopathology (2022)

CNVs identified in thyroid FNA cases are associated with Hürthle cell morphology and are suggestive of a neoplasm with Hürthle cell features in thyroid FNAs classified as FLUS-HCT/HCN. This finding may be helpful in triaging patients who would benefit from surgical management.

Keyphrases

copy number
single cell
cell therapy
mitochondrial dna
genome wide
fine needle aspiration
gene expression
cell death
cell cycle arrest