Asynchronous ventilation at 120 compared with 90 or 100 compressions per minute improves haemodynamic recovery in asphyxiated newborn piglets.

Sparsh PatelPo-Yin CheungTze-Fun LeeMatteo P PasquinMin LuMegan O'ReillyGeorg Marcus Schmölzer

Published in: Archives of disease in childhood. Fetal and neonatal edition (2019)

Although there was no difference between the groups in achieving ROSC, the haemodynamic recovery of CCaV+120 was significantly improved compared with CCaV+90 and CCaV+100, which were also associated with higher cerebral inflammatory and brain injury markers.

Keyphrases

brain injury
subarachnoid hemorrhage
cerebral ischemia
oxidative stress
cardiopulmonary resuscitation
mechanical ventilation
blood brain barrier
acute respiratory distress syndrome