Repeated exposure to methamphetamine induces sex-dependent hypersensitivity to ischemic injury in the adult rat heart.
Boyd R RorabaughSarah L SeeleyThorne S StoopsManoranjan S D'SouzaPublished in: PloS one (2017)
Exposure of adult rats to methamphetamine sex-dependently increases the extent of myocardial injury following an ischemic insult. These data suggest that women who have a heart attack might be at risk of more extensive myocardial injury if they have a recent history of methamphetamine abuse.
Keyphrases
- heart failure
- ischemia reperfusion injury
- atrial fibrillation
- polycystic ovary syndrome
- electronic health record
- oxidative stress
- cerebral ischemia
- childhood cancer
- big data
- type diabetes
- pregnancy outcomes
- machine learning
- young adults
- pregnant women
- adipose tissue
- skeletal muscle
- subarachnoid hemorrhage
- blood brain barrier