Adjuvant chemotherapy versus concurrent chemoradiotherapy for high-risk cervical cancer after radical hysterectomy and systematic lymphadenectomy.
Munetaka TakekumaYuka KasamatsuNobuhiro KadoShiho KujiAki TanakaNobutaka TakahashiMasakazu AbeYasuyuki HirashimaPublished in: International journal of clinical oncology (2016)
Chemotherapy after surgery for high-risk patients had similar efficacy and a different toxicity profile compared with CCRT, and a more radical surgical procedure would improve the survival outcome. However, CCRT was associated with worse toxicity than CT. We advocate a prospective randomized study to compare CT with CCRT for patients with high-risk factors for recurrence.
Keyphrases
- locally advanced
- end stage renal disease
- computed tomography
- image quality
- newly diagnosed
- oxidative stress
- chronic kidney disease
- ejection fraction
- dual energy
- rectal cancer
- contrast enhanced
- early stage
- peritoneal dialysis
- lymph node
- prognostic factors
- free survival
- squamous cell carcinoma
- positron emission tomography
- radiation therapy
- neoadjuvant chemotherapy
- sentinel lymph node
- magnetic resonance
- pet ct