A Comprehensive Flow Cytometry Panel for Analysis of Idiopathic Subglottic Stenosis.

Raymond J SoSamuel L CollinsYee Chan-LiIoan LinaAlexander GelbardKevin M MotzAlexander T Hillel

Published in: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (2024)

We present a comprehensive flow cytometry panel for iSGS. This flow panel may serve as a common platform among airway scientists to elucidate the cellular mechanisms underpinning iSGS and other upper airway pathologies. Scar iSGS samples demonstrate a distinct cellular profile relative to normal iSGS specimens, exhibiting increased fibroblast, endothelial, and inflammatory cell types but decreased epithelium.

Keyphrases

flow cytometry
single cell
cell therapy
high throughput
oxidative stress
endothelial cells
stem cells
wound healing
bone marrow