Login / Signup

URB597 abrogates anxiogenic and depressive behaviors in the methamphetamine-withdrawal mice: Role of the cannabinoid receptor type 1, cannabinoid receptor type 2, and transient receptor potential vanilloid 1 channels.

Mohaddeseh Ebrahimi-GhiriFatemeh KhakpaiMohammad-Reza Zarrindast
Published in: Journal of psychopharmacology (Oxford, England) (2020)
The results suggest that URB597 has a potential for preventing methamphetamine withdrawal-evoked anxiety and depression. Cannabinoid type 1 receptors, cannabinoid type 2 receptors and transient receptor potential vanilloid 1 differently affect depression-related behaviors in methamphetamine-withdrawal mice treated with URB597.
Keyphrases
  • binding protein
  • high fat diet induced
  • bipolar disorder
  • cerebral ischemia
  • adipose tissue
  • skeletal muscle
  • brain injury
  • blood brain barrier
  • stress induced