Safety and Efficacy of Hybrid Cooperative Complexes of Sodium Hyaluronate and Sodium Chondroitin for the Treatment of Patients with Symptomatic Knee Osteoarthritis.

Cristiano SconzaDario RomanoDalila ScaturroGiulia Letizia MauroGiulia LeonardiAngelo AlitoStefano RespizziElizaveta KonBerardo Di Matteo

Published in: Rheumatology and therapy (2024)

A single intraarticular HA-SC injection was safe, well-tolerated, and did not lead to major deterioration in terms of reducing knee pain, stiffness, and physical function limitation in patients with symptomatic KOA.

Keyphrases

knee osteoarthritis
chronic pain
pain management
neuropathic pain
total knee arthroplasty
ultrasound guided
spinal cord injury
combination therapy
smoking cessation
replacement therapy