Bacterial etiology of sputum from tuberculosis suspected patients and antibiogram of the isolates.
Ramesh Sharma RegmiSujan KhadkaSanjeep SapkotaSanjib AdhikariKhuma Kumari DhakalBishnu DhakalBandana LamsalSarad Chandra KaflePublished in: BMC research notes (2020)
Bacterial growth was recovered in 47% (71/150) of the TB suspected patients of which 12.66% (19/150) had pulmonary TB infection. Streptococcus spp. (9%) and Pseudomonas aeruginosa (9%) were the most frequently isolated bacteria. Enterobacteriaceae accounted for 35% of the total isolates. Occurrence of bacterial pathogens was more in males (69%) than in females (31%).The incidence of bacterial pathogen was seen associated with gender of the patients and with the TB infection (p < 0.05) but independent with age of the patients and HIV infection (p > 0.05). Tetracycline was effective against Streptococcus spp. whereas gentamicin was effective against Bacillus species. Imipenem and co-trimoxazole were effective drugs for Gram-negative isolates. Among 83 isolates, 35 were multi-drug resistant, 9 were ESBL producers and 4 were MBL producers.
Keyphrases
- end stage renal disease
- drug resistant
- pseudomonas aeruginosa
- chronic kidney disease
- newly diagnosed
- ejection fraction
- mycobacterium tuberculosis
- emergency department
- peritoneal dialysis
- cystic fibrosis
- pulmonary embolism
- patient reported outcomes
- pulmonary hypertension
- human immunodeficiency virus
- candida albicans
- genetic diversity
- hiv aids