Effect of ethyl gallate and propyl gallate on dextran sulfate sodium (DSS)-induced ulcerative colitis in C57BL/6 J mice: preventive and protective.

Priyanka Raju ChouguleRajendra SangarajuPradeep B PatilS S Y H QadriVirendra V PanpatilSudip GhoshSathish Kumar MungamuriManjula BhanooriSukesh Narayan Sinha

Published in: Inflammopharmacology (2023)

Our study highlights the protective effect of ethyl gallate and propyl gallate in various combinations which, in pre-clinical animals, serve as an anti-inflammatory drug against the severe form of colitis, indicating its potential for the treatment of IBD in humans. In addition, propyl gallate was investigated for the first time in this study for its anti-colitogenic effect with normal drinking water and reduced effect with copper water.

Keyphrases

drinking water
ulcerative colitis
anti inflammatory
early onset
drug induced
health risk assessment
emergency department
type diabetes
ionic liquid
metabolic syndrome
skeletal muscle
heavy metals
adverse drug
high resolution
stress induced