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Metabolic syndrome in pregnancy and risk for adverse pregnancy outcomes: A prospective cohort of nulliparous women.

Jessica A GriegerTina Bianco-MiottoLuke E GrzeskowiakShalem Y LeemaqzLucilla PostonLesley M E McCowanLouise C KennyJenny E MyersJames J WalkerGus A DekkerClaire T Roberts
Published in: PLoS medicine (2018)
We did not compare the impact of individual metabolic components with that of MetS as a composite, and therefore cannot conclude that MetS is better at identifying women at risk. However, more than half of the women who had MetS in early pregnancy developed a pregnancy complication compared with just over a third of women who did not have MetS. Furthermore, while increasing BMI increases the probability of GDM, the addition of MetS exacerbates this probability. Further studies are required to determine if individual MetS components act synergistically or independently.
Keyphrases
  • pregnancy outcomes
  • pregnant women
  • polycystic ovary syndrome
  • metabolic syndrome
  • breast cancer risk
  • insulin resistance
  • cardiovascular disease
  • adipose tissue
  • uric acid
  • cardiovascular risk factors