Effects of oral appliances on serum cytokines in adults with obstructive sleep apnea: a systematic review.
Paulo Mecenas Alves Farias-JuniorGiza Hellen Nonato MirandaNathalia Carolina Fernandes FagundesDavid NormandoKarina Correa Flexa RibeiroPublished in: Sleep & breathing = Schlaf & Atmung (2021)
Although limited, existing scientific evidence showed that OA therapy may improve serum cytokine levels in adults with OSA. However, short treatment periods are not effective in reducing markers of systemic inflammation which may require extended time and a decrease of in apneic events to improve.