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T-cell response to phytohemagglutinin in the interferon-γ release assay as a potential biomarker for the response to immune checkpoint inhibitors in patients with non-small cell lung cancer.

Chisato KamimakiNobuaki KobayashMomo HirataKohei SomekawaNobuhiko FukudaSousuke KuboSeigo KatakuraShuhei TeranishiKeisuke WatanabeNobuyuki HoritaYu HaraMasaki YamamotoMakoto KudoHongmei PiaoTakeshi Kaneko
Published in: Thoracic cancer (2021)
The T-SPOT.TB assay can be used to quantify the number of immunospots in response to antigen stimulation, which may predict the response to immune checkpoint inhibitors in patients with non-small cell lung cancer.
Keyphrases
  • high throughput
  • mycobacterium tuberculosis
  • dendritic cells
  • immune response