The Role of Tight Junctions in Atopic Dermatitis: A Systematic Review.

Spyridoula Katsarou Michael MakrisEfstratios VakirlisStamatios Gregoriou

Published in: Journal of clinical medicine (2023)

Dysfunction of TJs and their components, especially claudins, have a significant role in the pathogenesis and vicious circle of inflammation in AD. Discovering more basic science data regarding TJ functionality may be the key for the use of specific/targeted therapies in order to improve epidermal barrier function in AD.

Keyphrases

atopic dermatitis
oxidative stress
blood brain barrier
public health
electronic health record
single molecule
big data
wound healing
machine learning