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Tumor downstaging as an intermediate endpoint to assess the activity of neoadjuvant systemic therapy in patients with muscle-invasive bladder cancer.

Alberto MartiniRachel JiaBart S FerketNikhil WaingankarElizabeth R PlimackSimon J CrabbLauren C HarshmanEvan Y YuThomas PowlesJonathan E RosenbergSumanta Kumar PalUlka N VaishampayanAndrea NecchiN Peter WiklundReza MehrazinMadhu MazumdarJohn P SfakianosMatthew D Galsky
Published in: Cancer (2019)
A decrease of at least 1 stage from the cT stage to the pT stage is associated with improved OS in patients with MIBC treated with NAC.
Keyphrases
  • muscle invasive bladder cancer
  • computed tomography
  • rectal cancer
  • transcription factor
  • stem cells
  • radiation therapy
  • mesenchymal stem cells