Expansion of CD45RA-FOXP3++ regulatory T cells is associated with immune tolerance in patients with combined kidney and bone marrow transplantation.
Yeongbeen KwonKyo Won LeeYou Min KimHyojun ParkMin Kyung JungYoung Joon ChoiJin Kyung SonJuHee HongSu-Hyung ParkGhee Young KwonHeejin YooKyunga KimSung Joo KimJae Berm ParkEui-Cheol ShinPublished in: Clinical & translational immunology (2021)
Thus, our findings propose a biomarker that can distinguish CKBMT patients who achieve transplant tolerance and are eligible for discontinuation of immunosuppressants and may provide insight into tolerance mechanisms in CKBMT.