Scutellarein attenuates atopic dermatitis by selectively inhibiting transient receptor potential vanilloid 3 channels.

Yujing WangLiaoxi TanKejun JiaoChu XueQinglian TangShan JiangYounan RenHao ChenTarek Mohamed Abd El-AzizKhalid N M AbdelazeemYe YuFang ZhaoMichael Xi Zhu Zheng-Yu Cao

Published in: British journal of pharmacology (2022)

Collectively, these data demonstrate that Scu ameliorates carvacrol-induced skin inflammation by directly inhibiting TRPV3, and TRPV3 represents a viable therapeutic target for AD treatment.

Keyphrases

atopic dermatitis
signaling pathway
oxidative stress
neuropathic pain
high glucose
diabetic rats
electronic health record
soft tissue
mouse model
big data
cerebral ischemia
spinal cord injury
wound healing
endothelial cells
spinal cord
artificial intelligence
climate change