Vascular miR-181b controls tissue factor-dependent thrombogenicity and inflammation in type 2 diabetes.

Marco WitkowskiMario WitkowskiMona SaffarzadehJulian FriebelTermeh TabaraieLoc Ta BaoAritra ChakrabortyAndrea DörnerBernd StratmannDiethelm TschoepeSamantha J WinterAndreas KruegerWolfram RufUlf LandmesserUrsula Rauch

Published in: Cardiovascular diabetology (2020)

miR-181b epigenetically controls the procoagulant state in diabetes. Reduced miR-181b levels contribute to increased thrombogenicity and may help to identify individuals at particular risk for thrombosis.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
oxidative stress
pulmonary embolism
insulin resistance
long noncoding rna