Adipose triglyceride lipase gene expression in peripheral blood mononuclear cells of subjects with obesity and its association with insulin resistance, inflammation and lipid accumulation in liver.

Samira Ezzati-MobaserSahar YarahmadiNikta Dadkhah NikrooMohammad Hasan MalekiZeynab YousefiPegah GolpourMona NourbakhshMitra Nourbakhsh

Published in: Obesity science & practice (2023)

Obesity and MetS were associated with dysregulation of ATGL. ATGL might play a role in the upregulation of inflammatory cytokines and act as a significant contributor to the development of metabolic abnormalities related to obesity.

Keyphrases

insulin resistance
metabolic syndrome
high fat diet induced
gene expression
adipose tissue
type diabetes
high fat diet
weight loss
skeletal muscle
polycystic ovary syndrome
weight gain
oxidative stress
cell proliferation
physical activity
long non coding rna