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Approach for defining human adenovirus infection and disease for central review adjudication in clinical studies.

Brian T FisherJesse BlumenstockCraig L K BogeSydney ShusterAlix E SeifMichael GreenMarian G MichaelsJessie L AlexanderMonica I ArduraTamara P MillerDiego R HijanoWilliam J MullerJennifer E SchusterAbby M GreenDaniel E DulekAdriana E KajonLara A Danziger-Isakov
Published in: Pediatric transplantation (2024)
Application of definitions by a CRC for a study of HAdV infection and disease is feasible and can provide consistency in the assignment of outcomes. Definitions need further refinement to improve reproducibility and to provide guidance on determining clinical improvement or worsening after initial diagnosis of HAdV infection or disease.
Keyphrases
  • endothelial cells
  • type diabetes
  • adipose tissue